10 Iconic Brother And Sister Cartoon Characters Duo

Big brother and little sister duo Tanjiro and Nezuko are one of the most loved siblings in anime. The duo are the main leads of the show Demon Slayer.

Tanjiro and Nezuko are the only remaining Kamado family member after their family was killed by a demon. During the tragic incident, Nezuko is turned into a demon but surprisingly she showcases signs of human emotion and thought.

Despite Nezuko's demon transition the bond between the brother and sister isn't affected. Tanjiro's main goal in the series is to find a cure and restore Nezuko's humanity. Tanjiro's determination to save his little sister drives him to become a demon slayer.

On the other hand, Nezuko tries to protect her older brother with her newfound demonic abilities. The young girl suppresses her demonic instincts with the help and support of Tanjiro.

Bart and Lisa Simpsons are known to be the famous animated siblings duo of the television world. Bart is two years older than his little sister Lisa.

Bart is known to be a sharp wit and mischievous rebel while Lisa has an intelligent and politically aware personality.  They share a similar trait of being rebellious toward their parents.

They are known to be the typical brother and sister as they don't get along well. But there are times when the two of them understand each other and sympathize and act like they are best friends.

Bart and Lisa have a younger sibling named Maggie.

Avatar: The Last Airbender is named one of the greatest shows on American Television. The features the famous duo Sokka and Katara.

The show follows the journey of the last airbender named Aang along with his friends Katara, Sokka, and Toph to end Fire Nation's war with others. As the show goes on we get to see the bond between the popular siblings.

Sokka and Katara have different personalities from one another. The older brother Sokka has a cynical and comedic personality while Katara is gentle and compassionate. But despite those differences, they support each other through hardships.

Leo and Annie have an adorable bond with each other. The two of the share passion for art and music.

Annie is a cheerful girl who loves to sing and spend time with her friends. Leo is the group leader whose main talent is conducting. Leo's most prized possession is his father's, Conductor Baton.

Leo is a protective older brother who takes care of Annie and also watches over her. He even teaches her to pilot his rocket ship. Through their shared passion, the duo inspires and encourages each other.

Kick and his little sister Brianna have a love-hate relationship with one another. The Buttowskis are two years apart from each other.

Brianna is known to be a spoiled kid who often competes in beauty pageants and recitals while Kick is a stubborn and hard-headed kid who aspires to become the world's best daredevil.

Like every other little sibling, Brianna teases her brother Kick about his real birth name and is often seen taking things that are precious to him. She also has a mutual respect for him and helps Kick occasionally.

Kick and Brianna have an older brother named Brad who is also known to be the secondary antagonist of the show.

Little brother and Big sister duo in cartoon is none other than Dee Dee and Dexter.

They are one of the most nostalgic characters from the Cartoon Network show. Siblings around the world can relate to the characters.

Dee Dee is a ditzy, energetic, and mischievous teenager while Dexter is an intelligent boy who just wants to get the work done. Dexter has a secret laboratory filled with his great inventions but somehow Dee Dee gains access to his laboratory despite his great attempts to keep her out.

Once inside the goofy teenager plays with her young brother's gadgets which leads to destruction. Despite Dexter's annoyance with Dee Dee, the young one feels a reluctant affection for her.

Emmy and Max are the siblings who enter the magical realm of the dragon world with the help of the magical dragon scale.  In the dragon land, they befriend a group of dragons.

As an older sister, Emmy takes a protective and nurturing role toward Max as she guides him through their adventures in dragon land. Sometimes, Max struggles to be the youngest in his friend circle as he isn't able to do things as his pals. 

However, he looks up to his elder sister for approval. One of the themes of the show is the bond between Emmy and Max and how they support each other during difficult times.

Judy and Elroy relationship depicts the typical sibling bond of support, love, and occasional sibling rivalry. Judy and Elroy have an age gap of ten years.

Elroy is a genius and an expert in all space science. He is also fond of robotics and gadgets. His elder sister Judy encourages Elroy to his inventions and offers guidance and advice whenever the young one is in trouble.

The Jetsons live in the futuristic year 2062 with robotic contraptions, holograms, whimsical inventions, and aliens.

Mabel and Dipper are twins but it is known that Mabel was born first. The siblings live with their uncle over the summer in the mysterious town known as Gravity Falls.

Dipper's character is compassionate, intelligent, rational, and self-conscious while Mabel's personality is fun, energetic, and free-spirited. During their stay in Gravity Falls the twins discover that things are not what they seem in the town.

With the help of the mysterious journal Mabel and Dipper unravel the town's secrets each day. The twins and their friends work together as a team using their skills and qualities to solve the mystery.

Jazz and Danny relationship showcases an overprotective sister and her helpless little brother. The duo's perspective towards each other changes as the show goes on.

The two of them were quite close when they were young kids. Their relationship became strained when Jazz began to act snobbish, annoying, bossy, overprotective, and too mature for her own good.

Due to her change in personality, Danny couldn't confide in her even though Jazz tried to bond with him. Jazz's attitude toward Danny begins to change when she witnesses her younger sibling transforming into his ghostly alter ego.

Jazz never revealed his secrets and waited for him to share them with her. Eventually, the secrets help the siblings bond with each other again.